Chloromycetin in the Treatment of Cholera
نویسندگان
چکیده
Since the advent of sulphonamides chemotherapy of cholera lias been intensely studied, but it has not yielded any uniform results. These drugs have been tried generally with the usual saline treatment but the outcome has been nothing like the dramatic effect as seen in bacillary dysentery. Fonno-cibazol was expected to be somewhat more effective but its value appears to be limited. Recently Chloromycetin has been shown by Gauld ct al. (1949) in in vitro and in vivo experiment tests to inhibit completely the growth of Inaba and Ogawa strains of V. cholera. This observation prompted us to undertake a clinical trial of this
منابع مشابه
A Comparative Study of Phthalylsulphathiazol, Chloromycetin and Aureomycin in the Treatment of Cholera
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Treatment of Cholera with Oral and Intravenous Chloromycetin *From the Clinical Research Unit, Indian Council of Medical Research, at the School of Tropical Medicine, Calcutta, in collaboration with the Bacteriology Department of the School and with Cholera Ward, Nilratan Sarkar Medical College Hospital, Calcutta.
rate as compared with the control series. In 1951 a further small series of patients (unpublished) were treated with the drug more or less in the same dosage (about 12 gm., in divided doses for 3 days) but as it was not well tolerated, the trial was discontinued. Terramycin appeared to be better tolerated, but the effect of treatment with it was practically similar to that of Chloromycetin and ...
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